The evolutionary history of ACE2 usage within the coronavirus subgenus Sarbecovirus

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SARS-CoV-1 and SARS-CoV-2 are not phylogenetically closely related; however, both use the ACE2 receptor in humans for cell entry. This is not a universal sarbecovirus trait; for example, many known sarbecoviruses related to SARS-CoV-1 have two deletions in the receptor binding domain of the spike pr...

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Detalles Bibliográficos
Autores principales: Wells, H.L, Letko, M, Lasso, G, Ssebide, B, Nziza, J, Byarugaba, D.K, Navarrete-Macias, I, Liang, E, Cranfield, M, Han, B.A, Tingley, M.W, Diuk-Wasser, M, Goldstein, T, Johnson, C.K, Mazet, J, Chandran, K, Munster, V.J, Gilardi, K, Anthony, S.J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359528/
https://www.ncbi.nlm.nih.gov/pubmed/32676605
http://dx.doi.org/10.1101/2020.07.07.190546

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