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SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques
CD4 T follicular helper (T(fh)) cells are important for the generation of long-lasting and specific humoral protection against viral infections. The degree to which SARS-CoV-2 infection generates T(fh) cells and stimulates the germinal center response is an important question as we investigate vacci...
Autores principales: | Elizaldi, Sonny R., Lakshmanappa, Yashavanth Shaan, Roh, Jamin W., Schmidt, Brian A., Carroll, Timothy D., Weaver, Kourtney D., Smith, Justin C., Deere, Jesse D., Dutra, Joseph, Stone, Mars, Sammak, Rebecca Lee, Olstad, Katherine J., Reader, J. Rachel, Ma, Zhong-Min, Nguyen, Nancy K., Watanabe, Jennifer, Usachaenko, Jodie, Immareddy, Ramya, Yee, JoAnn L., Weiskopf, Daniela, Sette, Alessandro, Hartigan-O’Connor, Dennis, McSorley, Stephen J., Morrison, John H., Tran, Nam K., Simmons, Graham, Busch, Michael P, Kozlowski, Pamela A., Van Rompay, Koen K.A., Miller, Christopher J., Iyer, Smita S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359530/ https://www.ncbi.nlm.nih.gov/pubmed/32676606 http://dx.doi.org/10.1101/2020.07.07.191007 |
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