Estimating the establishment of local transmission and the cryptic phase of the COVID-19 pandemic in the USA

We use a global metapopulation transmission model to study the establishment of sustained and undetected community transmission of the COVID-19 pandemic in the United States. The model is calibrated on international case importations from mainland China and takes into account travel restrictions to...

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Detalles Bibliográficos
Autores principales: Davis, Jessica T., Chinazzi, Matteo, Perra, Nicola, Mu, Kunpeng, Piontti, Ana Pastore y, Ajelli, Marco, Dean, Natalie E., Gioannini, Corrado, Litvinova, Maria, Merler, Stefano, Rossi, Luca, Sun, Kaiyuan, Xiong, Xinyue, Halloran, M. Elizabeth, Longini, Ira M., Viboud, Cécile, Vespignani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359534/
https://www.ncbi.nlm.nih.gov/pubmed/32676609
http://dx.doi.org/10.1101/2020.07.06.20140285
Descripción
Sumario:We use a global metapopulation transmission model to study the establishment of sustained and undetected community transmission of the COVID-19 pandemic in the United States. The model is calibrated on international case importations from mainland China and takes into account travel restrictions to and from international destinations. We estimate widespread community transmission of SARS-CoV-2 in February, 2020. Modeling results indicate international travel as the key driver of the introduction of SARS-CoV-2 in the West and East Coast metropolitan areas that could have been seeded as early as late-December, 2019. For most of the continental states the largest contribution of imported infections arrived through domestic travel flows.

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