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Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids
All lifeforms have developed highly sophisticated systems equipped to detect altered self and non-self nucleic acids (NA). In vertebrates, NA-sensing receptors safeguard the integrity of the organism by detecting pathogens, dyshomeostasis and damage, and inducing appropriate responses to eliminate p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Published by Elsevier Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359798/ https://www.ncbi.nlm.nih.gov/pubmed/32668228 http://dx.doi.org/10.1016/j.immuni.2020.06.014 |