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A Novel LC‐MS/MS Assay for Quantification of Des‐carboxy Prothrombin and Characterization of Warfarin‐Induced Changes

Warfarin is a narrow therapeutic index anticoagulant drug and its use is associated with infrequent but significant adverse bleeding events. The international normalized ratio (INR) is the most commonly used biomarker to monitor and titrate warfarin therapy. However, INR is derived from a functional...

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Detalles Bibliográficos
Autores principales:	Basit, Abdul, Prasad, Bhagwat, Estergreen, Joanne K., Sabath, Daniel E., Alade, Nathan, Veenstra, David L., Rettie, Allan E., Thummel, Kenneth E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359935/ https://www.ncbi.nlm.nih.gov/pubmed/32004415 http://dx.doi.org/10.1111/cts.12757

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