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Open Data Revolution in Clinical Research: Opportunities and Challenges
Efforts for sharing individual clinical data are gaining momentum due to a heightened recognition that integrated data sets can catalyze biomedical discoveries and drug development. Among the benefits are the fact that data sharing can help generate and investigate new research hypothesis beyond tho...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359943/ https://www.ncbi.nlm.nih.gov/pubmed/32004409 http://dx.doi.org/10.1111/cts.12756 |
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author | Shahin, Mohamed H. Bhattacharya, Sanchita Silva, Diego Kim, Sarah Burton, Jackson Podichetty, Jagdeep Romero, Klaus Conrado, Daniela J. |
author_facet | Shahin, Mohamed H. Bhattacharya, Sanchita Silva, Diego Kim, Sarah Burton, Jackson Podichetty, Jagdeep Romero, Klaus Conrado, Daniela J. |
author_sort | Shahin, Mohamed H. |
collection | PubMed |
description | Efforts for sharing individual clinical data are gaining momentum due to a heightened recognition that integrated data sets can catalyze biomedical discoveries and drug development. Among the benefits are the fact that data sharing can help generate and investigate new research hypothesis beyond those explored in the original study. Despite several accomplishments establishing public systems and guidance for data sharing in clinical trials, this practice is not the norm. Among the reasons are ethical challenges, such as privacy of individuals, data ownership, and control. This paper creates awareness of the potential benefits and challenges of sharing individual clinical data, how to overcome these challenges, and how as a clinical pharmacology community we can shape future directions in this field. |
format | Online Article Text |
id | pubmed-7359943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73599432020-07-17 Open Data Revolution in Clinical Research: Opportunities and Challenges Shahin, Mohamed H. Bhattacharya, Sanchita Silva, Diego Kim, Sarah Burton, Jackson Podichetty, Jagdeep Romero, Klaus Conrado, Daniela J. Clin Transl Sci Reviews Efforts for sharing individual clinical data are gaining momentum due to a heightened recognition that integrated data sets can catalyze biomedical discoveries and drug development. Among the benefits are the fact that data sharing can help generate and investigate new research hypothesis beyond those explored in the original study. Despite several accomplishments establishing public systems and guidance for data sharing in clinical trials, this practice is not the norm. Among the reasons are ethical challenges, such as privacy of individuals, data ownership, and control. This paper creates awareness of the potential benefits and challenges of sharing individual clinical data, how to overcome these challenges, and how as a clinical pharmacology community we can shape future directions in this field. John Wiley and Sons Inc. 2020-03-10 2020-07 /pmc/articles/PMC7359943/ /pubmed/32004409 http://dx.doi.org/10.1111/cts.12756 Text en © 2020 The Authors. Clinical and Translational Science published by Wiley Periodicals, Inc. on behalf of the American Society for Clinical Pharmacology and Therapeutics. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Reviews Shahin, Mohamed H. Bhattacharya, Sanchita Silva, Diego Kim, Sarah Burton, Jackson Podichetty, Jagdeep Romero, Klaus Conrado, Daniela J. Open Data Revolution in Clinical Research: Opportunities and Challenges |
title | Open Data Revolution in Clinical Research: Opportunities and Challenges |
title_full | Open Data Revolution in Clinical Research: Opportunities and Challenges |
title_fullStr | Open Data Revolution in Clinical Research: Opportunities and Challenges |
title_full_unstemmed | Open Data Revolution in Clinical Research: Opportunities and Challenges |
title_short | Open Data Revolution in Clinical Research: Opportunities and Challenges |
title_sort | open data revolution in clinical research: opportunities and challenges |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359943/ https://www.ncbi.nlm.nih.gov/pubmed/32004409 http://dx.doi.org/10.1111/cts.12756 |
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