Cargando…

Efficacy of All-Trans-Retinoic Acid in High-Risk Acute Myeloid Leukemia with Overexpression of EVI1

INTRODUCTION: EVI1 (MECOM)-positive acute myeloid leukemia (AML) cells have shown in vitro sensitivity to all-trans-retinoic acid (ATRA) by inducing differentiation, cell death, and decreased leukemic engraftment. METHODS: In this pilot study, we investigated the response to ATRA in 13 high-risk AML...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paubelle, Etienne, Plesa, Adriana, Hayette, Sandrine, Elhamri, Mohamed, Zylbersztejn, Florence, Hermine, Olivier, Salles, Gilles, Thomas, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359977/ https://www.ncbi.nlm.nih.gov/pubmed/32699982 http://dx.doi.org/10.1007/s40487-019-0095-9

Ejemplares similares

The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid
por: Steinmetz, Birgit, et al.
Publicado: (2014)

High frequency of CD34+CD38-/low immature leukemia cells is correlated with unfavorable prognosis in acute myeloid leukemia
por: Plesa, Adriana, et al.
Publicado: (2017)

Prognostic Value of Genetic Alterations in Elderly Patients with Acute Myeloid Leukemia: A Single Institution Experience
por: Heiblig, Maël, et al.
Publicado: (2019)

All-trans retinoic acid enhances, and a pan-RAR antagonist counteracts, the stem cell promoting activity of EVI1 in acute myeloid leukemia
por: Nguyen, Chi Huu, et al.
Publicado: (2019)

Treatment with Low-Dose Cytarabine in Elderly Patients (Age 70 Years or Older) with Acute Myeloid Leukemia: A Single Institution Experience
por: Heiblig, Maël, et al.
Publicado: (2016)

Donor-Derived Leukemia in a Recipient of Double-Unit Cord Blood Transplantation for Acute Myeloid Leukemia: A Case Study and Literature Review
por: Plesa, Adriana, et al.
Publicado: (2022)

Evi1 Counteracts Anti-Leukemic and Stem Cell Inhibitory Effects of All-Trans Retinoic Acid on Flt3-ITD/Npm1c-Driven Acute Myeloid Leukemia Cells
por: Nguyen, Chi Huu, et al.
Publicado: (2020)

Bone Marrow Necrosis in Newly Diagnosed Acute Leukemia: Two Case Reports and Review of the Literature
por: Quintela, Adrien, et al.
Publicado: (2017)

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
por: Boutzen, Héléna, et al.
Publicado: (2016)

Tipifarnib in the treatment of acute myeloid leukemia
por: Thomas, Xavier, et al.
Publicado: (2007)

High DNA Methyltransferase DNMT3B Levels: A Poor Prognostic Marker in Acute Myeloid Leukemia
por: Hayette, Sandrine, et al.
Publicado: (2012)

Deferasirox and Vitamin D Improves Overall Survival in Elderly Patients with Acute Myeloid Leukemia after Demethylating Agents Failure
por: Paubelle, Etienne, et al.
Publicado: (2013)

Targeting of myeloid-derived suppressor cells by all-trans retinoic acid as host-directed therapy for human tuberculosis
por: Leukes, Vinzeigh N., et al.
Publicado: (2021)

Pharmacokinetics of All‐trans Retinoic Acid in Pediatric Patients with Leukemia
por: Takitani, Kimitaka, et al.
Publicado: (1995)

Transdifferentiation of Myoblasts Into Adipocytes by All-Trans-Retinoic Acid in Avian
por: Kim, Dong-Hwan, et al.
Publicado: (2022)

Potential Therapeutic Effect of All-Trans Retinoic Acid on Atherosclerosis
por: Deng, Qile, et al.
Publicado: (2022)

Deregulation of All-Trans Retinoic Acid Signaling and Development in Cancer
por: Brown, Geoffrey
Publicado: (2023)

High EVI1 Expression due to NRIP1/EVI1 Fusion in Therapy-related Acute Myeloid Leukemia: Description of the First Pediatric Case
por: D’Angiò, Mariella, et al.
Publicado: (2020)

EVI1 dysregulation: impact on biology and therapy of myeloid malignancies
por: Birdwell, Christine, et al.
Publicado: (2021)

All-Trans Retinoic Acid Activity in Acute Myeloid Leukemia: Role of Cytochrome P450 Enzyme Expression by the Microenvironment
por: Su, Meng, et al.
Publicado: (2015)

Decitabine combined with all-trans retinoic acid as treatment in a case of primary myelofibrosis transforming into acute myeloid leukaemia
por: Lin, Yan, et al.
Publicado: (2019)

All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells
por: Kim, Yundeok, et al.
Publicado: (2020)

Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells
por: Armstrong, J L, et al.
Publicado: (2005)

All-Trans Retinoic Acid in Combination with Primaquine Clears Pneumocystis Infection
por: Lei, Guang-Sheng, et al.
Publicado: (2013)

Emerging Cancer Epigenetic Mechanisms Regulated by All-Trans Retinoic Acid
por: Rossetti, Stefano, et al.
Publicado: (2020)

All trans retinoic acid as a host-directed immunotherapy for tuberculosis
por: Bahlool, Ahmad Z., et al.
Publicado: (2022)

All-Trans Retinoic Acid plus Arsenic Trioxide versus All-Trans Retinoic Acid plus Chemotherapy for Newly Diagnosed Acute Promyelocytic Leukemia: A Meta-Analysis
por: Ma, Yafang, et al.
Publicado: (2016)

Hepatic retinoic acid receptor alpha mediates all‐trans retinoic acid's effect on diet‐induced hepatosteatosis
por: Cassim Bawa, Fathima N., et al.
Publicado: (2022)

The combination of valproic acid, all-trans retinoic acid and low-dose cytarabine as disease-stabilizing treatment in acute myeloid leukemia
por: Fredly, Hanne, et al.
Publicado: (2013)

The Addition of All-Trans Retinoic Acid to Chemotherapy May Not Improve the Outcome of Patient with NPM1 Mutated Acute Myeloid Leukemia
por: Nazha, Aziz, et al.
Publicado: (2013)

All-Trans Retinoic Acid Enhances Matrix Metalloproteinase 2 Expression and Secretion in Human Myeloid Leukemia THP-1 Cells
por: Vu, Hien Thi, et al.
Publicado: (2018)

All-trans retinoic acid in non-promyelocytic acute myeloid leukemia: driver lesion dependent effects on leukemic stem cells
por: Nguyen, Chi H., et al.
Publicado: (2020)

All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism
por: Benjamin, Dalyia N., et al.
Publicado: (2022)

Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia
por: Glass, Carolyn, et al.
Publicado: (2013)

S116: CELLULAR AND MOLECULAR MECHANISMS OF EVI1-EXPRESSING MLL-REARRANGED ACUTE MYELOID LEUKEMIA
por: Châtel-Soulet, Hugues-Etienne, et al.
Publicado: (2022)

Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia
por: Tanaka, Atsushi, et al.
Publicado: (2022)

EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription
por: Ayoub, Edward, et al.
Publicado: (2018)

All-trans retinoic acid upregulates VEGF expression in glioma cells in vitro
por: Liang, Chen, et al.
Publicado: (2013)

Nanoparticle delivery and combination therapy of gambogic acid and all-trans retinoic acid
por: Yao, Jing, et al.
Publicado: (2014)

All-trans-retinoic acid–induced pseudotumor cerebri in acute promyelocytic leukemia
por: Anoop, T. M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qpb27srhubpopo7f35goumg9ac