Genome-wide transcriptomics identifies an early preclinical signature of prion infection

The clinical course of prion diseases is accurately predictable despite long latency periods, suggesting that prion pathogenesis is driven by precisely timed molecular events. We constructed a searchable genome-wide atlas of mRNA abundance and splicing alterations during the course of disease in pri...

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Detalles Bibliográficos
Autores principales: Sorce, Silvia, Nuvolone, Mario, Russo, Giancarlo, Chincisan, Andra, Heinzer, Daniel, Avar, Merve, Pfammatter, Manuela, Schwarz, Petra, Delic, Mirzet, Müller, Micha, Hornemann, Simone, Sanoudou, Despina, Scheckel, Claudia, Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360066/
https://www.ncbi.nlm.nih.gov/pubmed/32598380
http://dx.doi.org/10.1371/journal.ppat.1008653

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