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Sleep is bi-directionally modified by amyloid beta oligomers
Disrupted sleep is a major feature of Alzheimer’s disease (AD), often arising years before symptoms of cognitive decline. Prolonged wakefulness exacerbates the production of amyloid-beta (Aβ) species, a major driver of AD progression, suggesting that sleep loss further accelerates AD through a vicio...
Autores principales: | Özcan, Güliz Gürel, Lim, Sumi, Leighton, Patricia LA, Allison, W Ted, Rihel, Jason |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360368/ https://www.ncbi.nlm.nih.gov/pubmed/32660691 http://dx.doi.org/10.7554/eLife.53995 |
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