R-loops coordinate with SOX2 in regulating reprogramming to pluripotency

R-loops modulate genome stability and regulate gene expression, but the functions and the regulatory mechanisms of R-loops in stem cell biology are still unclear. Here, we profiled R-loops during somatic cell reprogramming and found that dynamic changes in R-loops are essential for reprogramming and...

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Detalles Bibliográficos
Autores principales: Li, Yaoyi, Song, Yawei, Xu, Wei, Li, Qin, Wang, Xinxiu, Li, Kuan, Wang, Juehan, Liu, Zicong, Velychko, Sergiy, Ye, Rong, Xia, Qing, Wang, Lei, Guo, Rong, Dong, Xiaotao, Zheng, Zhikai, Dai, Yushuang, Li, Haojie, Yao, Mingze, Xue, Yuanchao, Schöler, Hans R., Sun, Qianwen, Yao, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360481/
https://www.ncbi.nlm.nih.gov/pubmed/32704541
http://dx.doi.org/10.1126/sciadv.aba0777

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