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GBA3: a polymorphic pseudogene in humans that experienced repeated gene loss during mammalian evolution
The gene encoding the cytosolic β-glucosidase GBA3 shows pseudogenization due to a truncated allele (rs358231) that is polymorphic in humans. Since this enzyme is involved in the transformation of many plant β-glycosides, this particular case of gene loss may have been influenced by dietary adaptati...
Autores principales: | Lopes-Marques, Monica, Serrano, Catarina, Cardoso, Ana R., Salazar, Renato, Seixas, Susana, Amorim, António, Azevedo, Luisa, Prata, Maria J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360587/ https://www.ncbi.nlm.nih.gov/pubmed/32665690 http://dx.doi.org/10.1038/s41598-020-68106-y |
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