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Characterization of multicellular breast tumor spheroids using image data-driven biophysical mathematical modeling

Multicellular tumor spheroid (MCTS) systems provide an in vitro cell culture model system which mimics many of the complexities of an in vivo solid tumor and tumor microenvironment, and are often used to study cancer cell growth and drug efficacy. Here, we present a coupled experimental-computationa...

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Detalles Bibliográficos
Autores principales: Bowers, Haley J., Fannin, Emily E., Thomas, Alexandra, Weis, Jared A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360601/
https://www.ncbi.nlm.nih.gov/pubmed/32665565
http://dx.doi.org/10.1038/s41598-020-68324-4