HIF-1α is involved in blood–brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis

Bacterial meningitis is a deadly disease most commonly caused by Streptococcus pneumoniae, leading to severe neurological sequelae including cerebral edema, seizures, stroke, and mortality when untreated. Meningitis is initiated by the transfer of S. pneumoniae from blood to the brain across the blo...

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Detalles Bibliográficos
Autores principales: Devraj, Gayatri, Guérit, Sylvaine, Seele, Jana, Spitzer, Daniel, Macas, Jadranka, Khel, Maryam I., Heidemann, Roxana, Braczynski, Anne K., Ballhorn, Wibke, Günther, Stefan, Ogunshola, Omolara O., Mittelbronn, Michel, Ködel, Uwe, Monoranu, Camelia M., Plate, Karl H., Hammerschmidt, Sven, Nau, Roland, Devraj, Kavi, Kempf, Volkhard A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360668/
https://www.ncbi.nlm.nih.gov/pubmed/32529267
http://dx.doi.org/10.1007/s00401-020-02174-2

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