NK Cells Negatively Regulate CD8 T Cells to Promote Immune Exhaustion and Chronic Toxoplasma gondii Infection

NK cells regulate CD4+ and CD8+ T cells in acute viral infection, vaccination, and the tumor microenvironment. NK cells also become exhausted in chronic activation settings. The mechanisms causing these ILC responses and their impact on adaptive immunity are unclear. CD8+ T cell exhaustion develops...

Descripción completa

Detalles Bibliográficos
Autores principales: Ivanova, Daria L., Krempels, Ryan, Denton, Stephen L., Fettel, Kevin D., Saltz, Giandor M., Rach, David, Fatima, Rida, Mundhenke, Tiffany, Materi, Joshua, Dunay, Ildiko R., Gigley, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360721/
https://www.ncbi.nlm.nih.gov/pubmed/32733814
http://dx.doi.org/10.3389/fcimb.2020.00313

Ejemplares similares

Ejemplares similares