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Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells

Inspired by recent proteomic data demonstrating the upregulation of carbon and glycogen metabolism in aging human hematopoietic stem and progenitor cells (HPCs, CD34+ cells), this report addresses whether this is caused by elevated glycolysis of the HPCs on a per cell basis, or by a subpopulation th...

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Detalles Bibliográficos
Autores principales:	Poisa-Beiro, Laura, Thoma, Judith, Landry, Jonathan, Sauer, Sven, Yamamoto, Akihisa, Eckstein, Volker, Romanov, Natalie, Raffel, Simon, Hoffmann, Georg F., Bork, Peer, Benes, Vladimir, Gavin, Anne-Claude, Tanaka, Motomu, Ho, Anthony D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360735/ https://www.ncbi.nlm.nih.gov/pubmed/32665666 http://dx.doi.org/10.1038/s41598-020-68396-2

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