Genomic imprinting analyses identify maternal effects as a cause of phenotypic variability in type 1 diabetes and rheumatoid arthritis

Imprinted genes, giving rise to parent-of-origin effects (POEs), have been hypothesised to affect type 1 diabetes (T1D) and rheumatoid arthritis (RA). However, maternal effects may also play a role. By using a mixed model that is able to simultaneously consider all kinds of POEs, the importance of P...

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Detalles Bibliográficos
Autores principales: Blunk, Inga, Thomsen, Hauke, Reinsch, Norbert, Mayer, Manfred, Försti, Asta, Sundquist, Jan, Sundquist, Kristina, Hemminki, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360775/
https://www.ncbi.nlm.nih.gov/pubmed/32665606
http://dx.doi.org/10.1038/s41598-020-68212-x

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