Characterization of a Novel Compound That Stimulates STING-Mediated Innate Immune Activity in an Allele-Specific Manner

The innate immune response to cytosolic DNA involves transcriptional activation of type I interferons (IFN-I) and proinflammatory cytokines. This represents the culmination of intracellular signaling pathways that are initiated by pattern recognition receptors that engage DNA and require the adaptor...

Descripción completa

Detalles Bibliográficos
Autores principales: Abraham, Jinu, Botto, Sara, Mizuno, Nobuyo, Pryke, Kara, Gall, Bryan, Boehm, Dylan, Sali, Tina M., Jin, Haihong, Nilsen, Aaron, Gough, Michael, Baird, Jason, Chakhtoura, Marita, Subra, Caroline, Trautmann, Lydie, Haddad, Elias K., DeFilippis, Victor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360819/
https://www.ncbi.nlm.nih.gov/pubmed/32733475
http://dx.doi.org/10.3389/fimmu.2020.01430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360819/
https://www.ncbi.nlm.nih.gov/pubmed/32733475
http://dx.doi.org/10.3389/fimmu.2020.01430

Ejemplares similares