T-Cell Receptor CDR3 Loop Conformations in Solution Shift the Relative Vα-Vβ Domain Distributions

T-cell receptors are an important part in the adaptive immune system as they are responsible for detecting foreign proteins presented by the major histocompatibility complex (MHC). The affinity is predominantly determined by structure and sequence of the complementarity determining regions (CDRs), o...

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Detalles Bibliográficos
Autores principales: Fernández-Quintero, Monica L., Pomarici, Nancy D., Loeffler, Johannes R., Seidler, Clarissa A., Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360859/
https://www.ncbi.nlm.nih.gov/pubmed/32733478
http://dx.doi.org/10.3389/fimmu.2020.01440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360859/
https://www.ncbi.nlm.nih.gov/pubmed/32733478
http://dx.doi.org/10.3389/fimmu.2020.01440

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