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Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT(1A)-Mediated cAMP Signaling

BACKGROUND: Major depressive disorder (MDD) is a severe mental disorder related to the deficiency of monoamine neurotransmitters, particularly to abnormalities of 5-HT (5-hydroxytryptamine, serotonin) and its receptors. Our previous study suggested that acute treatment with a novel curcumin derivati...

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Detalles Bibliográficos
Autores principales: Li, Jianxin, Chen, Ling, Li, Gaowen, Chen, Xiaojuan, Hu, Sisi, Zheng, Liang, Luria, Victor, Lv, Jinpeng, Sun, Yindi, Xu, Ying, Yu, Yingcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360862/
https://www.ncbi.nlm.nih.gov/pubmed/32733195
http://dx.doi.org/10.3389/fnins.2020.00701

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