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Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT(1A)-Mediated cAMP Signaling
BACKGROUND: Major depressive disorder (MDD) is a severe mental disorder related to the deficiency of monoamine neurotransmitters, particularly to abnormalities of 5-HT (5-hydroxytryptamine, serotonin) and its receptors. Our previous study suggested that acute treatment with a novel curcumin derivati...
Autores principales: | Li, Jianxin, Chen, Ling, Li, Gaowen, Chen, Xiaojuan, Hu, Sisi, Zheng, Liang, Luria, Victor, Lv, Jinpeng, Sun, Yindi, Xu, Ying, Yu, Yingcong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360862/ https://www.ncbi.nlm.nih.gov/pubmed/32733195 http://dx.doi.org/10.3389/fnins.2020.00701 |
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