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SERINC5 Potently Restricts Retrovirus Infection In Vivo

The serine incorporator (SERINC) proteins are multipass transmembrane proteins that affect sphingolipid and phosphatidylserine synthesis. Human SERINC5 and SERINC3 were recently shown to possess antiretroviral activity for a number of retroviruses, including human immunodeficiency virus (HIV), murin...

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Detalles Bibliográficos
Autores principales: Timilsina, Uddhav, Umthong, Supawadee, Lynch, Brian, Stablewski, Aimee, Stavrou, Spyridon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360926/
https://www.ncbi.nlm.nih.gov/pubmed/32665269
http://dx.doi.org/10.1128/mBio.00588-20