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New Multidrug Efflux Inhibitors for Gram-Negative Bacteria
Active efflux of antibiotics preventing their accumulation to toxic intracellular concentrations contributes to clinically relevant multidrug resistance. Inhibition of active efflux potentiates antibiotic activity, indicating that efflux inhibitors could be used in combination with antibiotics to re...
Autores principales: | Marshall, Robert L., Lloyd, Georgina S., Lawler, Amelia J., Element, Sarah J., Kaur, Jaswant, Ciusa, Maria Laura, Ricci, Vito, Tschumi, Andreas, Kühne, Holger, Alderwick, Luke J., Piddock, Laura J. V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360932/ https://www.ncbi.nlm.nih.gov/pubmed/32665275 http://dx.doi.org/10.1128/mBio.01340-20 |
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