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Feedback regulation of heat shock factor 1 (Hsf1) activity by Hsp70‐mediated trimer unzipping and dissociation from DNA

The heat shock response is a universal transcriptional response to proteotoxic stress orchestrated by heat shock transcription factor Hsf1 in all eukaryotic cells. Despite over 40 years of intense research, the mechanism of Hsf1 activity regulation remains poorly understood at the molecular level. I...

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Detalles Bibliográficos
Autores principales:	Kmiecik, Szymon W, Le Breton, Laura, Mayer, Matthias P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360973/ https://www.ncbi.nlm.nih.gov/pubmed/32490574 http://dx.doi.org/10.15252/embj.2019104096

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