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Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway
The alarm cytokine interleukin‐1β (IL‐1β) is a potent activator of the inflammatory cascade following pathogen recognition. IL‐1β production typically requires two signals: first, priming by recognition of pathogen‐associated molecular patterns leads to the production of immature pro‐IL‐1β; subseque...
Autores principales: | Ipseiz, Natacha, Pickering, Robert J, Rosas, Marcela, Tyrrell, Victoria J, Davies, Luke C, Orr, Selinda J, Czubala, Magdalena A, Fathalla, Dina, Robertson, Avril AB, Bryant, Clare E, O'Donnell, Valerie, Taylor, Philip R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360975/ https://www.ncbi.nlm.nih.gov/pubmed/32484988 http://dx.doi.org/10.15252/embj.2019103454 |
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