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Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice
INTRODUCTION: Mesenchymal stromal cell (MSC) therapy mitigates lung injury and improves survival in murine models of sepsis. Precise mechanisms of therapeutic benefit remain poorly understood. OBJECTIVES: To identify host-derived regulatory elements that may contribute to the therapeutic effects of...
Autores principales: | Younes, Nadim, Zhou, Louis, Amatullah, Hajera, Mei, Shirley H J, Herrero, Raquel, Lorente, Jose Angel, Stewart, Duncan J, Marsden, Philip, Liles, W Conrad, Hu, Pingzhao, dos Santos, Claudia C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361025/ https://www.ncbi.nlm.nih.gov/pubmed/32546573 http://dx.doi.org/10.1136/thoraxjnl-2019-213561 |
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