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Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay

In this comparative biomarker study, we analysed 1768 serial sputum samples from 178 patients at 4 sites in Southeast Africa. We show that tuberculosis Molecular Bacterial Load Assay (TB-MBLA) reduces time-to-TB-bacillary-load-result from days/weeks by culture to hours and detects early patient trea...

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Detalles Bibliográficos
Autores principales: Sabiiti, Wilber, Azam, Khalide, Farmer, Eoghan Charles William, Kuchaka, Davis, Mtafya, Bariki, Bowness, Ruth, Oravcova, Katarina, Honeyborne, Isobella, Evangelopoulos, Dimitrios, McHugh, Timothy Daniel, Khosa, Celso, Rachow, Andrea, Heinrich, Norbert, Kampira, Elizabeth, Davies, Geraint, Bhatt, Nilesh, Ntinginya, Elias N, Viegas, Sofia, Jani, Ilesh, Kamdolozi, Mercy, Mdolo, Aaron, Khonga, Margaret, Boeree, Martin J, Phillips, Patrick P J, Sloan, Derek, Hoelscher, Michael, Kibiki, Gibson, Gillespie, Stephen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361026/
https://www.ncbi.nlm.nih.gov/pubmed/32354738
http://dx.doi.org/10.1136/thoraxjnl-2019-214238