High altitude reduces infection rate of COVID-19 but not case-fatality rate

Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID-19 infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was r...

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Autores principales: Segovia-Juarez, Jose, Castagnetto, Jesús M., Gonzales, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361094/
https://www.ncbi.nlm.nih.gov/pubmed/32679369
http://dx.doi.org/10.1016/j.resp.2020.103494
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author Segovia-Juarez, Jose
Castagnetto, Jesús M.
Gonzales, Gustavo F.
author_facet Segovia-Juarez, Jose
Castagnetto, Jesús M.
Gonzales, Gustavo F.
author_sort Segovia-Juarez, Jose
collection PubMed
description Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID-19 infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was recorded on March 6th, 2020. By June 13, 2020 there were 6498 deaths, and 224,132 SARS-CoV-2 positives. Using data from 185 capitals of provinces with altitudes ranging from 3 to 4342 m, we confirm previous reports that infection with COVID-19 at high altitude is reduced. However, case-fatality rate is not dependent of altitude. We have also presented first evidence that female protection towards death by COVID-19 is reduced as altitude of residence increases.
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spelling pubmed-73610942020-07-15 High altitude reduces infection rate of COVID-19 but not case-fatality rate Segovia-Juarez, Jose Castagnetto, Jesús M. Gonzales, Gustavo F. Respir Physiol Neurobiol Article Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID-19 infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was recorded on March 6th, 2020. By June 13, 2020 there were 6498 deaths, and 224,132 SARS-CoV-2 positives. Using data from 185 capitals of provinces with altitudes ranging from 3 to 4342 m, we confirm previous reports that infection with COVID-19 at high altitude is reduced. However, case-fatality rate is not dependent of altitude. We have also presented first evidence that female protection towards death by COVID-19 is reduced as altitude of residence increases. Elsevier B.V. 2020-10 2020-07-15 /pmc/articles/PMC7361094/ /pubmed/32679369 http://dx.doi.org/10.1016/j.resp.2020.103494 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Segovia-Juarez, Jose
Castagnetto, Jesús M.
Gonzales, Gustavo F.
High altitude reduces infection rate of COVID-19 but not case-fatality rate
title High altitude reduces infection rate of COVID-19 but not case-fatality rate
title_full High altitude reduces infection rate of COVID-19 but not case-fatality rate
title_fullStr High altitude reduces infection rate of COVID-19 but not case-fatality rate
title_full_unstemmed High altitude reduces infection rate of COVID-19 but not case-fatality rate
title_short High altitude reduces infection rate of COVID-19 but not case-fatality rate
title_sort high altitude reduces infection rate of covid-19 but not case-fatality rate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361094/
https://www.ncbi.nlm.nih.gov/pubmed/32679369
http://dx.doi.org/10.1016/j.resp.2020.103494
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