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Therapeutic targeting of JAKs: from hematology to rheumatology and from the first to the second generation of JAK inhibitors
Several cytokines and growth factors, as well as their downstream signalling pathways, are implicated in the pathogenesis of haematological and immune-mediated diseases. These mediators act through binding to their cognate receptor and activation of one or more of the four Janus family tyrosine kina...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Mediterranean Journal of Rheumatology (MJR)
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361188/ https://www.ncbi.nlm.nih.gov/pubmed/32676568 http://dx.doi.org/10.31138/mjr.31.1.105 |