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MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation
Mitochondrial function is critically dependent on the folding of the mitochondrial inner membrane into cristae; indeed, numerous human diseases are associated with aberrant crista morphologies. With the MICOS complex, OPA1 and the F(1)F(o)‐ATP synthase, key players of cristae biogenesis have been id...
Autores principales: | Stephan, Till, Brüser, Christian, Deckers, Markus, Steyer, Anna M, Balzarotti, Francisco, Barbot, Mariam, Behr, Tiana S, Heim, Gudrun, Hübner, Wolfgang, Ilgen, Peter, Lange, Felix, Pacheu‐Grau, David, Pape, Jasmin K, Stoldt, Stefan, Huser, Thomas, Hell, Stefan W, Möbius, Wiebke, Rehling, Peter, Riedel, Dietmar, Jakobs, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361284/ https://www.ncbi.nlm.nih.gov/pubmed/32567732 http://dx.doi.org/10.15252/embj.2019104105 |
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