High percentage of smudge cells in a patient with COVID19: Rediscovering their utility

We present a patient with SARS‐CoV‐2 infection, with an unexpected presence of lymphocytosis. Examination of blood film revealed mature small lymphocytes associated with high percentage of smudge cells (63%). A peripheral flow cyometry evidenced a CD5 negative CLL. A high percentage of smudge cells...

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Detalles Bibliográficos
Autores principales: Jerez, Joaquín, Ernst, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Covid‐19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361876/
https://www.ncbi.nlm.nih.gov/pubmed/32838400
http://dx.doi.org/10.1002/jha2.52
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author Jerez, Joaquín
Ernst, Daniel M.
author_facet Jerez, Joaquín
Ernst, Daniel M.
author_sort Jerez, Joaquín
collection PubMed
description We present a patient with SARS‐CoV‐2 infection, with an unexpected presence of lymphocytosis. Examination of blood film revealed mature small lymphocytes associated with high percentage of smudge cells (63%). A peripheral flow cyometry evidenced a CD5 negative CLL. A high percentage of smudge cells is associated with CLL diagnosis and has an important prognostic value: better survival and prolonged time to first treatment. It is a useful index in developing countries with low access to molecular testing.
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spelling pubmed-73618762020-07-15 High percentage of smudge cells in a patient with COVID19: Rediscovering their utility Jerez, Joaquín Ernst, Daniel M. EJHaem Covid‐19 We present a patient with SARS‐CoV‐2 infection, with an unexpected presence of lymphocytosis. Examination of blood film revealed mature small lymphocytes associated with high percentage of smudge cells (63%). A peripheral flow cyometry evidenced a CD5 negative CLL. A high percentage of smudge cells is associated with CLL diagnosis and has an important prognostic value: better survival and prolonged time to first treatment. It is a useful index in developing countries with low access to molecular testing. John Wiley and Sons Inc. 2020-07-03 /pmc/articles/PMC7361876/ /pubmed/32838400 http://dx.doi.org/10.1002/jha2.52 Text en © 2020 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Covid‐19
Jerez, Joaquín
Ernst, Daniel M.
High percentage of smudge cells in a patient with COVID19: Rediscovering their utility
title High percentage of smudge cells in a patient with COVID19: Rediscovering their utility
title_full High percentage of smudge cells in a patient with COVID19: Rediscovering their utility
title_fullStr High percentage of smudge cells in a patient with COVID19: Rediscovering their utility
title_full_unstemmed High percentage of smudge cells in a patient with COVID19: Rediscovering their utility
title_short High percentage of smudge cells in a patient with COVID19: Rediscovering their utility
title_sort high percentage of smudge cells in a patient with covid19: rediscovering their utility
topic Covid‐19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361876/
https://www.ncbi.nlm.nih.gov/pubmed/32838400
http://dx.doi.org/10.1002/jha2.52
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