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Holistic View on Cell Survival and DNA Damage: How Model-Based Data Analysis Supports Exploration of Dynamics in Biological Systems

In this work, a method is established to calibrate a model that describes the basic dynamics of DNA damage and repair. The model can be used to extend planning for radiotherapy and hyperthermia in order to include the biological effects. In contrast to “syntactic” models (e.g., describing molecular...

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Detalles Bibliográficos
Autores principales:	Weyland, Mathias S., Thumser-Henner, Pauline, Nytko, Katarzyna J., Rohrer Bley, Carla, Ulzega, Simone, Petri-Fink, Alke, Lattuada, Marco, Füchslin, Rudolf M., Scheidegger, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361897/ https://www.ncbi.nlm.nih.gov/pubmed/32695215 http://dx.doi.org/10.1155/2020/5972594

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