Less Reactive Thiol Ligands: Key towards Highly Mucoadhesive Drug Delivery Systems

As less reactive s-protected thiomers can likely interpenetrate the mucus gel layer to a higher extent before getting immobilized via disulfide bond formation with mucins, it was the aim of this study to develop a novel type of s-protected thiomer based on the less reactive substructure cysteine-N-a...

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Detalles Bibliográficos
Autores principales: Shahzadi, Iram, Fürst, Andrea, Akkus-Dagdeviren, Zeynep Burcu, Arshad, Shumaila, Kurpiers, Markus, Matuszczak, Barbara, Bernkop-Schnürch, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362194/
https://www.ncbi.nlm.nih.gov/pubmed/32486313
http://dx.doi.org/10.3390/polym12061259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362194/
https://www.ncbi.nlm.nih.gov/pubmed/32486313
http://dx.doi.org/10.3390/polym12061259

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