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Less Reactive Thiol Ligands: Key towards Highly Mucoadhesive Drug Delivery Systems
As less reactive s-protected thiomers can likely interpenetrate the mucus gel layer to a higher extent before getting immobilized via disulfide bond formation with mucins, it was the aim of this study to develop a novel type of s-protected thiomer based on the less reactive substructure cysteine-N-a...
Autores principales: | Shahzadi, Iram, Fürst, Andrea, Akkus-Dagdeviren, Zeynep Burcu, Arshad, Shumaila, Kurpiers, Markus, Matuszczak, Barbara, Bernkop-Schnürch, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362194/ https://www.ncbi.nlm.nih.gov/pubmed/32486313 http://dx.doi.org/10.3390/polym12061259 |
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