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Microglia induce the transformation of A1/A2 reactive astrocytes via the CXCR7/PI3K/Akt pathway in chronic post-surgical pain

BACKGROUND: Activated astrocytes play important roles in chronic post-surgical pain (CPSP). Recent studies have shown reactive astrocytes are classified into A1 and A2 phenotypes, but their precise roles in CPSP remain unknown. In this study, we investigated the roles of spinal cord A1 and A2 astroc...

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Detalles Bibliográficos
Autores principales:	Li, Ting, Liu, Tongtong, Chen, Xuhui, Li, Li, Feng, Miaomiao, Zhang, Yue, Wan, Li, Zhang, Chuanhan, Yao, Wenlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362409/ https://www.ncbi.nlm.nih.gov/pubmed/32665021 http://dx.doi.org/10.1186/s12974-020-01891-5

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