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Structural elucidation, molecular docking, α-amylase and α-glucosidase inhibition studies of 5-amino-nicotinic acid derivatives

In this study, 5-amino-nicotinic acid derivatives (1–13) have been designed and synthesized to evaluate their inhibitory potential against α-amylase and α-glucosidase enzymes. The synthesized compounds (1–13) exhibited promising α-amylase and α-glucosidase activities. IC(50) values for α-amylase act...

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Detalles Bibliográficos
Autores principales:	Nawaz, Muhammad, Taha, Muhammad, Qureshi, Faiza, Ullah, Nisar, Selvaraj, Manikandan, Shahzad, Sumaira, Chigurupati, Sridevi, Waheed, Abdul, Almutairi, Fadiah Ammar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362424/ https://www.ncbi.nlm.nih.gov/pubmed/32685927 http://dx.doi.org/10.1186/s13065-020-00695-1

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