H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts

BACKGROUND: H3K27ac histone acetylome changes contribute to the phenotypic response in heart diseases, particularly in end-stage heart failure. However, such epigenetic alterations have not been systematically investigated in remodeled non-failing human hearts. Therefore, valuable insight into cardi...

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Detalles Bibliográficos
Autores principales: Pei, Jiayi, Harakalova, Magdalena, Treibel, Thomas A., Lumbers, R Thomas, Boukens, Bastiaan J., Efimov, Igor R., van Dinter, Jip T., González, Arantxa, López, Begoña, El Azzouzi, Hamid, van den Dungen, Noortje, van Dijk, Christian G. M., Krebber, Merle M., den Ruijter, Hester M., Pasterkamp, Gerard, Duncker, Dirk J., Nieuwenhuis, Edward E. S., de Weger, Roel, Huibers, Manon M., Vink, Aryan, Moore, Jason H., Moon, James C., Verhaar, Marianne C., Kararigas, Georgios, Mokry, Michal, Asselbergs, Folkert W., Cheng, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362435/
https://www.ncbi.nlm.nih.gov/pubmed/32664951
http://dx.doi.org/10.1186/s13148-020-00895-5

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