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BDNF reverses aging-related microglial activation

BACKGROUND: Excessive microglial activation is implicated in the pathogenesis of various age-related neurodegenerative diseases. In addition to neurons, brain-derived neurotrophic factor (BDNF) and its receptor TrkB are also expressed in microglia. However, the direct effect of BDNF on age-related m...

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Detalles Bibliográficos
Autores principales:	Wu, Shih-Ying, Pan, Bo-Syong, Tsai, Sheng-Feng, Chiang, Yi-Ting, Huang, Bu-Miin, Mo, Fan-E, Kuo, Yu-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362451/ https://www.ncbi.nlm.nih.gov/pubmed/32664974 http://dx.doi.org/10.1186/s12974-020-01887-1

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