ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer

BACKGROUND: Small cell lung cancer (SCLC) is a more aggressive subtype of lung cancer that often results in rapid tumor growth, early metastasis, and acquired therapeutic resistance. Consequently, such phenotypical characteristics of SCLC set limitations on viable procedural options, making it diffi...

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Detalles Bibliográficos
Autores principales: Szczepanski, Aileen Patricia, Zhao, Zibo, Sosnowski, Tori, Goo, Young Ah, Bartom, Elizabeth Thomas, Wang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362484/
https://www.ncbi.nlm.nih.gov/pubmed/32669118
http://dx.doi.org/10.1186/s13073-020-00760-3

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