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Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana

BACKGROUND: Artemisinin-based combination therapy (ACT) partner drugs, currently used in Ghana are lumefantrine, amodiaquine and piperaquine. Plasmodium falciparum isolates with reduced susceptibility to these partner drugs may affect treatment outcome. Mutations in pfmdr1 gene is linked to reduced...

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Detalles Bibliográficos
Autores principales:	Hodoameda, Peter, Duah-Quashie, Nancy Odurowah, Hagan, Charles Oheneba, Matrevi, Sena, Abuaku, Benjamin, Koram, Kwadwo, Quashie, Neils Ben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362516/ https://www.ncbi.nlm.nih.gov/pubmed/32669113 http://dx.doi.org/10.1186/s12936-020-03320-7

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