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Role of peroxisome proliferators-activated receptor-gamma in advanced glycation end product-mediated functional loss of voltage-gated potassium channel in rat coronary arteries

BACKGROUND: High blood glucose impairs voltage-gated K(+) (Kv) channel-mediated vasodilation in rat coronary artery smooth muscle cells (CSMCs) via oxidative stress. Advanced glycation end product (AGE) and receptor for AGE (RAGE) axis has been found to impair coronary dilation by reducing Kv channe...

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Detalles Bibliográficos
Autores principales:	Gao, Side, Hua, Bing, Liu, Qingbo, Liu, Huirong, Li, Weiping, Li, Hongwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362521/ https://www.ncbi.nlm.nih.gov/pubmed/32664860 http://dx.doi.org/10.1186/s12872-020-01613-y

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