CX3CL1/CX3CR1 axis attenuates early brain injury via promoting the delivery of exosomal microRNA-124 from neuron to microglia after subarachnoid hemorrhage

BACKGROUND: Microglial activation-mediated neuroinflammation is a major contributor to early brain injury (EBI) after subarachnoid hemorrhage (SAH). MicroRNA-124 (miR-124) is the most abundant miRNAs in the central nervous system (CNS) and plays a vital role in microglial activation by targeting pro...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Jiang, Ming, Li, Haiying, Wang, Yang, Shen, Haitao, Li, Xiang, Zhang, Yunhai, Wu, Jiang, Yu, Zhengquan, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362528/
https://www.ncbi.nlm.nih.gov/pubmed/32664984
http://dx.doi.org/10.1186/s12974-020-01882-6

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