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The unfolded protein response is activated in the olfactory system in Alzheimer’s disease

Olfactory dysfunction is an early and prevalent symptom of Alzheimer’s disease (AD) and the olfactory bulb is a nexus of beta-amyloid plaque and tau neurofibrillary tangle (NFT) pathology during early AD progression. To mitigate the accumulation of misfolded proteins, an endoplasmic reticulum stress...

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Detalles Bibliográficos
Autores principales:	Murray, Helen C., Dieriks, Birger Victor, Swanson, Molly E. V., Anekal, Praju Vikas, Turner, Clinton, Faull, Richard L. M., Belluscio, Leonardo, Koretsky, Alan, Curtis, Maurice A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362534/ https://www.ncbi.nlm.nih.gov/pubmed/32665027 http://dx.doi.org/10.1186/s40478-020-00986-7

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