A Perspective on Emerging Therapeutic Interventions for COVID-19

Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and e...

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Detalles Bibliográficos
Autores principales: Torequl Islam, Muhammad, Nasiruddin, Md., Khan, Ishaq N., Mishra, Siddhartha Kumar, Kudrat-E-Zahan, Md., Alam Riaz, Thoufiqul, Ali, Eunus S., Rahman, M. Safiur, Mubarak, Mohammad S., Martorell, Miquel, Cho, William C., Calina, Daniela, Docea, Anca Oana, Sharifi-Rad, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362761/
https://www.ncbi.nlm.nih.gov/pubmed/32733837
http://dx.doi.org/10.3389/fpubh.2020.00281
Descripción
Sumario:Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.

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