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A Perspective on Emerging Therapeutic Interventions for COVID-19
Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and e...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362761/ https://www.ncbi.nlm.nih.gov/pubmed/32733837 http://dx.doi.org/10.3389/fpubh.2020.00281 |
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author | Torequl Islam, Muhammad Nasiruddin, Md. Khan, Ishaq N. Mishra, Siddhartha Kumar Kudrat-E-Zahan, Md. Alam Riaz, Thoufiqul Ali, Eunus S. Rahman, M. Safiur Mubarak, Mohammad S. Martorell, Miquel Cho, William C. Calina, Daniela Docea, Anca Oana Sharifi-Rad, Javad |
author_facet | Torequl Islam, Muhammad Nasiruddin, Md. Khan, Ishaq N. Mishra, Siddhartha Kumar Kudrat-E-Zahan, Md. Alam Riaz, Thoufiqul Ali, Eunus S. Rahman, M. Safiur Mubarak, Mohammad S. Martorell, Miquel Cho, William C. Calina, Daniela Docea, Anca Oana Sharifi-Rad, Javad |
author_sort | Torequl Islam, Muhammad |
collection | PubMed |
description | Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed. |
format | Online Article Text |
id | pubmed-7362761 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73627612020-07-29 A Perspective on Emerging Therapeutic Interventions for COVID-19 Torequl Islam, Muhammad Nasiruddin, Md. Khan, Ishaq N. Mishra, Siddhartha Kumar Kudrat-E-Zahan, Md. Alam Riaz, Thoufiqul Ali, Eunus S. Rahman, M. Safiur Mubarak, Mohammad S. Martorell, Miquel Cho, William C. Calina, Daniela Docea, Anca Oana Sharifi-Rad, Javad Front Public Health Public Health Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed. Frontiers Media S.A. 2020-07-03 /pmc/articles/PMC7362761/ /pubmed/32733837 http://dx.doi.org/10.3389/fpubh.2020.00281 Text en Copyright © 2020 Torequl Islam, Nasiruddin, Khan, Mishra, Kudrat-E-Zahan, Alam Riaz, Ali, Rahman, Mubarak, Martorell, Cho, Calina, Docea and Sharifi-Rad. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Torequl Islam, Muhammad Nasiruddin, Md. Khan, Ishaq N. Mishra, Siddhartha Kumar Kudrat-E-Zahan, Md. Alam Riaz, Thoufiqul Ali, Eunus S. Rahman, M. Safiur Mubarak, Mohammad S. Martorell, Miquel Cho, William C. Calina, Daniela Docea, Anca Oana Sharifi-Rad, Javad A Perspective on Emerging Therapeutic Interventions for COVID-19 |
title | A Perspective on Emerging Therapeutic Interventions for COVID-19 |
title_full | A Perspective on Emerging Therapeutic Interventions for COVID-19 |
title_fullStr | A Perspective on Emerging Therapeutic Interventions for COVID-19 |
title_full_unstemmed | A Perspective on Emerging Therapeutic Interventions for COVID-19 |
title_short | A Perspective on Emerging Therapeutic Interventions for COVID-19 |
title_sort | perspective on emerging therapeutic interventions for covid-19 |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362761/ https://www.ncbi.nlm.nih.gov/pubmed/32733837 http://dx.doi.org/10.3389/fpubh.2020.00281 |
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