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A Perspective on Emerging Therapeutic Interventions for COVID-19

Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and e...

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Autores principales: Torequl Islam, Muhammad, Nasiruddin, Md., Khan, Ishaq N., Mishra, Siddhartha Kumar, Kudrat-E-Zahan, Md., Alam Riaz, Thoufiqul, Ali, Eunus S., Rahman, M. Safiur, Mubarak, Mohammad S., Martorell, Miquel, Cho, William C., Calina, Daniela, Docea, Anca Oana, Sharifi-Rad, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362761/
https://www.ncbi.nlm.nih.gov/pubmed/32733837
http://dx.doi.org/10.3389/fpubh.2020.00281
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author Torequl Islam, Muhammad
Nasiruddin, Md.
Khan, Ishaq N.
Mishra, Siddhartha Kumar
Kudrat-E-Zahan, Md.
Alam Riaz, Thoufiqul
Ali, Eunus S.
Rahman, M. Safiur
Mubarak, Mohammad S.
Martorell, Miquel
Cho, William C.
Calina, Daniela
Docea, Anca Oana
Sharifi-Rad, Javad
author_facet Torequl Islam, Muhammad
Nasiruddin, Md.
Khan, Ishaq N.
Mishra, Siddhartha Kumar
Kudrat-E-Zahan, Md.
Alam Riaz, Thoufiqul
Ali, Eunus S.
Rahman, M. Safiur
Mubarak, Mohammad S.
Martorell, Miquel
Cho, William C.
Calina, Daniela
Docea, Anca Oana
Sharifi-Rad, Javad
author_sort Torequl Islam, Muhammad
collection PubMed
description Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.
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spelling pubmed-73627612020-07-29 A Perspective on Emerging Therapeutic Interventions for COVID-19 Torequl Islam, Muhammad Nasiruddin, Md. Khan, Ishaq N. Mishra, Siddhartha Kumar Kudrat-E-Zahan, Md. Alam Riaz, Thoufiqul Ali, Eunus S. Rahman, M. Safiur Mubarak, Mohammad S. Martorell, Miquel Cho, William C. Calina, Daniela Docea, Anca Oana Sharifi-Rad, Javad Front Public Health Public Health Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed. Frontiers Media S.A. 2020-07-03 /pmc/articles/PMC7362761/ /pubmed/32733837 http://dx.doi.org/10.3389/fpubh.2020.00281 Text en Copyright © 2020 Torequl Islam, Nasiruddin, Khan, Mishra, Kudrat-E-Zahan, Alam Riaz, Ali, Rahman, Mubarak, Martorell, Cho, Calina, Docea and Sharifi-Rad. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Torequl Islam, Muhammad
Nasiruddin, Md.
Khan, Ishaq N.
Mishra, Siddhartha Kumar
Kudrat-E-Zahan, Md.
Alam Riaz, Thoufiqul
Ali, Eunus S.
Rahman, M. Safiur
Mubarak, Mohammad S.
Martorell, Miquel
Cho, William C.
Calina, Daniela
Docea, Anca Oana
Sharifi-Rad, Javad
A Perspective on Emerging Therapeutic Interventions for COVID-19
title A Perspective on Emerging Therapeutic Interventions for COVID-19
title_full A Perspective on Emerging Therapeutic Interventions for COVID-19
title_fullStr A Perspective on Emerging Therapeutic Interventions for COVID-19
title_full_unstemmed A Perspective on Emerging Therapeutic Interventions for COVID-19
title_short A Perspective on Emerging Therapeutic Interventions for COVID-19
title_sort perspective on emerging therapeutic interventions for covid-19
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362761/
https://www.ncbi.nlm.nih.gov/pubmed/32733837
http://dx.doi.org/10.3389/fpubh.2020.00281
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