The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching

Cutaneous wound healing is associated with the unpleasant sensation of itching. Here we investigated the mechanisms underlying this type of itch, focusing on the contribution of soluble factors released during healing. We found high amounts of interleukin 31 (IL-31) in skin wound tissue during the p...

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Detalles Bibliográficos
Autores principales: Xu, Junji, Zanvit, Peter, Hu, Lei, Tseng, Pang-Yen, Liu, Na, Wang, Fu, Liu, Ousheng, Zhang, Dunfang, Jin, Wenwen, Guo, Nancy, Han, Yichen, Yin, Jessica, Cain, Alexander, Hoon, Mark A., Wang, Songlin, Chen, WanJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362873/
https://www.ncbi.nlm.nih.gov/pubmed/32673566
http://dx.doi.org/10.1016/j.immuni.2020.06.023

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