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Apoptotic cells induce CD103 expression and immunoregulatory function in myeloid dendritic cell precursors through integrin α(v) and TGF-β activation
In the mammalian gut CD103+ve myeloid DCs are known to suppress inflammation threatened by luminal bacteria, but stimuli driving DC precursor maturation towards this beneficial phenotype are incompletely understood. We isolated CD11+ve DCs from mesenteric lymph nodes (MLNs) of healthy mice; CD103+ve...
Autores principales: | Zhang, Ailiang, Paidassi, Helena, Lacy-Hulbert, Adam, Savill, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363096/ https://www.ncbi.nlm.nih.gov/pubmed/32667911 http://dx.doi.org/10.1371/journal.pone.0232307 |
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