Detection of epidermal growth factor receptor T790M mutation by allele-specific loop mediated isothermal amplification

INTRODUCTION: Targeted therapy using specific inhibitors against tyrosine kinases (TKs) is a paradigm in non-small-cell lung cancer management. However, the success of TK inhibitor (TKI) therapy depends on certain activating or acquired mutations, which render sensitivity or resistance to TKIs in th...

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Detalles Bibliográficos
Autores principales: Arjuna, Srividya, Chakraborty, Gunimala, Venkataram, Rajesh, Dechamma, Pandyanda Nanjappa, Chakraborty, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363156/
https://www.ncbi.nlm.nih.gov/pubmed/32684851
http://dx.doi.org/10.4103/jcar.JCar_6_20

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