Pathogenic SREK1 decrease in Huntington’s disease lowers TAF1 mimicking X-linked dystonia parkinsonism

Huntington’s disease and X-linked dystonia parkinsonism are two monogenic basal ganglia model diseases. Huntington’s disease is caused by a polyglutamine-encoding CAG repeat expansion in the Huntingtin (HTT) gene leading to several toxic interactions of both the expanded CAG-containing mRNA and the...

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Detalles Bibliográficos
Autores principales: Hernández, Ivó H, Cabrera, Jorge R, Santos-Galindo, María, Sánchez-Martín, Manuel, Domínguez, Verónica, García-Escudero, Ramón, Pérez-Álvarez, María J, Pintado, Belén, Lucas, José J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363496/
https://www.ncbi.nlm.nih.gov/pubmed/32533168
http://dx.doi.org/10.1093/brain/awaa150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363496/
https://www.ncbi.nlm.nih.gov/pubmed/32533168
http://dx.doi.org/10.1093/brain/awaa150

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