Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease

Neurofilament light chain (NfL) is a protein that is selectively expressed in neurons. Increased levels of NfL measured in either cerebrospinal fluid or blood is thought to be a biomarker of neuronal damage in neurodegenerative diseases. However, there have been limited investigations relating NfL t...

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Autores principales: Schultz, Stephanie A., Strain, Jeremy F., Adedokun, Adedamola, Wang, Qing, Preische, Oliver, Kuhle, Jens, Flores, Shaney, Keefe, Sarah, Dincer, Aylin, Ances, Beau M., Berman, Sarah B., Brickman, Adam M., Cash, David M., Chhatwal, Jasmeer, Cruchaga, Carlos, Ewers, Michael, Fox, Nick N., Ghetti, Bernardino, Goate, Alison, Graff-Radford, Neill R., Hassenstab, Jason J., Hornbeck, Russ, Jack, Clifford, Johnson, Keith, Joseph-Mathurin, Nelly, Karch, Celeste M., Koeppe, Robert A., Lee, Athene K.W., Levin, Johannes, Masters, Colin, McDade, Eric, Perrin, Richard J., Rowe, Christopher C., Salloway, Stephen, Saykin, Andrew J., Sperling, Reisa, Su, Yi, Villemagne, Victor L., Vöglein, Jonathan, Weiner, Michael, Xiong, Chengjie, Fagan, Anne M., Morris, John C., Bateman, Randall J., Benzinger, Tammie L.S., Jucker, Mathias, Gordon, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363568/
https://www.ncbi.nlm.nih.gov/pubmed/32522711
http://dx.doi.org/10.1016/j.nbd.2020.104960

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