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MS2-TRIBE Evaluates Both Protein-RNA Interactions and Nuclear Organization of Transcription by RNA Editing

Both UV-cross-linking and immunoprecipitation (CLIP) and RNA editing (TRIBE) can identify the targets of RNA-binding proteins. To evaluate false-positives of CLIP and TRIBE, endogenous β-actin mRNA was tagged with MS2 stem loops, making it the only bona fide target mRNA for the MS2 capsid protein (M...

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Detalles Bibliográficos
Autores principales:	Biswas, Jeetayu, Rahman, Reazur, Gupta, Varun, Rosbash, Michael, Singer, Robert H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363692/ https://www.ncbi.nlm.nih.gov/pubmed/32674054 http://dx.doi.org/10.1016/j.isci.2020.101318

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