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Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ
The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteoporosis, and ectopic hair formation in the gingiva in Sox21...
Autores principales: | Saito, Kan, Michon, Frederic, Yamada, Aya, Inuzuka, Hiroyuki, Yamaguchi, Satoko, Fukumoto, Emiko, Yoshizaki, Keigo, Nakamura, Takashi, Arakaki, Makiko, Chiba, Yuta, Ishikawa, Masaki, Okano, Hideyuki, Thesleff, Irma, Fukumoto, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363706/ https://www.ncbi.nlm.nih.gov/pubmed/32674056 http://dx.doi.org/10.1016/j.isci.2020.101329 |
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